Anyone have stomach issues with NAC?

Hi everyone!!! Hoping to see if people had a similar reaction.

I just started taking NAC yesterday with my other supplements to knock this embedded e.coli UTI (2 2000 dmannose 3x a day/2 ellura 1x a day/biofilm disrupter 2x a day/probiotic 1x a day along with macrobid and amoxicillin for a sinus infection)

Has anyone had trouble before? I take them once in the morning and once at night and every time I just feel so so nauseous and lots of acid reflux.I can’t tell if this is because of the antibiotics or the new supplement I added in there.

Thanks so much! Been really loving this group and everyone’s insights.